Senior Software Engineer — MD Simulation Engineering - CA, Santa Clara, United States
$184,000 - $287,500 USD yearly
Originally posted 16 October 2026 by the employer. Relisted by the employer on 17 October 2026.
Build and optimize CUDA kernels for core molecular dynamics simulation primitives on NVIDIA BioNeMo.
About the role
The MD Simulation Engineering team builds GPU-native simulation software that powers molecular dynamics at scale within NVIDIA BioNeMo. The work spans kernel engineering, software architecture, and delivering high-performance math primitives across NVIDIA GPU generations.
What you'll do
- Build, implement, and optimize CUDA kernels for core MD simulation primitives. - Integrate simulation primitives into major MD engines. - Drive CI/CD infrastructure for multi-SKU kernel builds, automated performance regression testing, and cross-simulator validation across NVIDIA GPU generations. - Collaborate with Applied Science teams to evaluate new algorithms and translate research prototypes into production-quality, shipped software.
What you'll need
- 8+ years of software engineering experience with a strong background in CUDA and GPU programming. - Deep proficiency in C and C++, navigating and contributing to large, sophisticated codebases. - Strong foundation in high-performance computing. - Familiarity with molecular dynamics simulation concepts. - Experience building or contributing to scientific software libraries, simulation engines, or developer-facing GPU APIs. - BS/MS in Computer Science, Computational Science, Physics, Applied Mathematics, or a related field, or equivalent experience.
Skills: CUDA kernels, GPU programming, molecular dynamics simulation, scientific software, HPC, C/C++
This role has been open 152 days — well above the 55-day median for Infrastructure/Platform Software roles.
Infrastructure/Platform Software · GPU Software Stack
|
Open roles in category
242
|
Median days open
55 d
|
Median salary
$220k
|
See the full market breakdown ▾Category comparison, skills in demand, and who else is hiring
| Metric | NVIDIA | All employers we track in this specialty (242 roles · 20 employers) |
|---|---|---|
| Open roles in this specialty | 122 | 242 |
| Open roles in the wider Software, Firmware & Systems family | 997 | 6277 · 144 employers |
| Median days open | 57 d | 55 d (+2 d vs this employer) |
| Median salary (USD postings) | — | $220k |
Skills observed across this category: CUDA kernels, GPU programming, molecular dynamics simulation, scientific software, HPC, C/C++
Who's hiring in this category
- NVIDIA (this employer) · 120 open roles · median 57 d
- AMD · 52 open roles · median 53 d
- Intel Corporation · 25 open roles · median 14 d
- Qualcomm · 18 open roles · median 128 d
- Arm Holdings · 5 open roles · median 121 d
- Graphcore · 4 open roles · median 3 d
How we counted: 242 open Infrastructure/Platform Software (GPU Software Stack) roles from 20 employers tracked in the SemiconductorJobs index, counted 24 Oct 2026. Specialty figures count only roles carrying this exact specialty label, so an employer's related work in neighbouring specialties is not included there — it is counted in the wider Software, Firmware & Systems family row. Figures refresh nightly.